Cleanrooms are used to perform clean processes, so it’s counterintuitive to think of maintenance and repair activities inside a controlled environment. Yet, they are very necessary and performed quite often. Protocol for crews working inside a cleanroom is different than the typical office space: personnel must gown and adhere to strict clean processes, just like lab technicians. The equipment crews bring into the cleanroom must also be compatible with the required ISO rating. Slow, careful movements and meticulous control over dust and other contaminants are critical to prevent complete shut-down and time-consuming recertification of the room.
IsoDry desiccator cabinets are the latest, patent-pending innovation in desiccators from Terra Universal. Desiccators are containers designed to reduce relative humidity (RH) for moisture-sensitive stored items, either by purging the container consistently with nitrogen, using silica gel desiccants or pulling vacuum. The IsoDry desiccators use nitrogen to accomplish this task, both in achieving and maintaining a humidity “set-point.”
Pass-through chambers streamline workflow by giving personnel a fast, efficient way to transfer objects into, and out of, spaces with different ISO ratings. Facilities save man-hours and expense by avoiding time-consuming gowning. How else can pass-through chambers help the lab’s bottom line?
Transferring items into and out-out rooms is something we all take for granted. It’s easy to pick up a folder and deliver it to an office down the hall, or load up a cart with paperclips and staples destined for the supply cabinet. Once you work in a cleanroom, however, this simple task turns into a “process.” Strict requirements govern the steps that personnel take for otherwise simple actions.
Pharmacy compounders have a lot of factors to consider when making the decision to go into the business of mixing individual prescriptions, particularly those considered “hazardous.” It can be a lucrative operation, but one which is closely overseen. For good reason, though: mistakes in the recent past have taught us that sloppy procedures, partly resulting from a lack of regulations, can have deadly consequences.
Once you’ve make the commitment to move forward with your compounding pharmacy business model, you have to understand your responsibilities (and the associated costs) regarding equipment and furnishings. What used to be true for minimum “engineering controls” is no longer good enough, and regulators will make sure that pharmacies comply.
Particles, particles everywhere! What is a lab to do? Sources of these contaminating specks are many: equipment, room materials, unfiltered air, bacteria and mold, clothing, and (the biggest culprit of all) people. Facilities make heroic efforts to keep the adulterants at bay, but some amount of contaminants will find their way into the controlled space.