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Polymerase Chain Reaction - PCR

Scientists involved with forensics, drug development, disease identification and diagnoses, or genetic studies understand the value of Polymerase Chain Reaction (PCR). Cloning of target DNA and RNA sequences is possible using this technology that was only discovered in the mid-1980s. Especially useful for small samples or mere fragments, PCR is a process used to replicate, or amplify, specified gene sequences; researchers can study these sequences for additions, deletions or mutations related to genetic conditions or disease states. The process of PCR can be summarized as follows: 1) heat is applied to denature (separate) the nucleic acid strand; 2) a medium temperature causes primers to anneal, or join, with the newly-created template, and 3) cool temperature, combined with an enzyme, completes the elongation/extension of the strand. Now the newly created sample is stabilized with a chemical buffer and stored at near-freezing temperature. Synthesis and modification of genomic molecules allows scientists to accomplish more today than ever before, and with smaller sample sizes. Polymerase Chain Reaction helps scientists create critical samples for research. The equipment featured here were selected to help your purchasing efforts: a work station and thermal cyclers necessary for DNA segment replication; lab instruments to support the steps involved in amplification; and gowning and cleaning items to reduce contaminants.
Polymerase Chain Reaction - PCR
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