Converting an Office or Lab into a ISO 5, ISO 6, ISO 7 or ISO 8 Cleanroom
Facility managers who need classified cleanroom space generally face a difficult choice.
New construction requires a suitable site and can take months, even years, to complete. Depending on area requirements, installing a modular cleanroom inside an existing room is a faster, more economical alternative, but this room-within-a-room approach often creates unusable or inaccessible space.
Terra’s BioSafe Cleanroom Conversion System offers a more economical, space-efficient approach: converting an existing unclassified room into a cleanroom, using modular components to meet a wide range of environmental and access requirements.
Modular Ceiling Grid
This modular structure mounts directly to existing walls to form a drop ceiling, or rests on top of walls that have no ceiling. Its all-steel, interlocking design requires no external bracing (either column support or suspension cables) for spans up to 20 ft. (6096 mm). Larger spans entail a single internal support column or external ceiling support cable.
The grid's 2-foot x 4-foot (610 x 1220 mm) ceiling bays support cleanroom ceiling components: room-side replaceable HEPA fan/filter units (FFUs), LED or fluorescent lights, and polypropylene ceiling panels.
Terra’s WhisperFlow™ Room-Side Replaceable FFUs provide the vertical flow of micro-filtered air that removes contaminants inside the room. By selecting the proper quantity of FFUs, you can meet any cleanliness classification to ISO 5 (Class 100). Their design allows filter replacement from inside the cleanroom, without breaching the cleanroom ceiling. Lights and blank ceiling panels complete the ceiling structure. See additional information below.
BioSafe® Cleanroom Wall Systems
Our Class A fiberglass-reinforced plastic (FRP) panel system is the only one that is certified for use in ISO 5 cleanrooms. Applied with a non-outgassing polymer adhesive to nearly any wall surface, including gypsum wallboard, this material features a patented finish that creates a durable, noncontaminating surface that is highly resistant to chemicals and microbial growth. More economical Class C panel are available (see ordering information).
CPVC (chlorinated polyvinyl chloride) Class A wall panels also meet ISO 5 requirements. A solvent-free, non-outgassing adhesive adheres them to walls. Seams are welded to close all gaps and make this system a great choice for converting current building space into a cleanroom. CPVC resists damage from a broad range of chemicals, making clean-up faster and easier.
The links below provide more information on these and other components that comprise this system, including cleanroom doors, pass-through chambers, and flooring. Installation of smooth Class A BioSafe panels, with proper wall and ceiling coving, meets stringent ISO 5-6 and cGMP requirements for the most critical applications, including sterile processing. For less critical cleanroom requirements, consider FRP Class C panels.
Complete Pre-Sale and After-Sale Support
Whatever your applications, call Terra with your dimensional, cleanliness and other requirements. A configuration specialist will provide a complete quotation, including drawings, if applicable, and manufacturing time, on a system ready for installation and certification.
Terra performs BioSafe system installation and seismic analysis based on your facility. We also train and support local contractors on installation and permitting to local building code.*
Available Certified ISO Grade Designs: ISO 5, ISO 6, ISO 7, ISO 8
Time to completion is faster by utilizing prefabricated, pre-engineered cleanroom wall panels and components
uPVC laminated steel surface is robust, easy to clean, and resists corrosion, abrasive chemicals and detergents
Seamless transitions between ceiling, walls, and floors ensure an air-tight, closed system to prevent contamination influx
Fully-flush, smooth surface provides stick-built aesthetic using modular wall panels
Panels conform to ISO 14644 standards for ISO class 5 and below environments
Refer to sales order and/or drawings for dimensions and other details
Floors should be level before installation
Cleanroom Leveling Mechanism compensates for small variations in floor level to eliminate need for unsightly floor shims.
Since regulations vary considerably in different locations, Terra assumes no responsibility for meeting local building regulations, including fire and seismic codes
Check your local planning department to see what regulations apply to your installation
• Core Material: Aluminum Honeycomb
• Type: Wall Panel
• Panel Material: uPVC-Laminated Steel
• Available Certified ISO Grade Designs: ISO 5, ISO 6, ISO 7, ISO 8
BioSafe® cleanroom with exhaust plenum and ventilation systemBioSafe Containment CleanroomsBioSafe® cleanroom with exhaust plenum and ventilation system creates negative internal pressure for biohazard containment (shown with A/C units).
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Stick-Built Cleanroom for Electronics Assembly
Stick-Built, ISO 6 cleanroom for electronics assembly installed in San Diego, California
Brick-and-mortar, ISO 7 cleanroom for high-throughput packaging of medical devicesMedical Device Packaging CleanroomBrick-and-mortar, ISO 7 cleanroom for high-throughput packaging of medical devices
Tips for Passing ISO, cGMP, FDA and Other Certifications
Know your ISO requirement
A Terra product specialist can offer general design advice or make a consultation referral. Regulated industries such as pharmaceutical compounding maintain clear requirements for ISO cleanliness and related cleanroom characteristics. Other operations may require a certification consultant to specify these design requirements based on specific operations being performed.
Either way, make sure you know the applicable performance requirements before you select a room design or cleanliness level.
FFU Ceiling Coverage and Air Change Rate
ISO specifies permissible particle counts for each cleanliness level but not how many fan/filter units are required to meet these target values. Other organizations, including the Institute for Environmental Science, provide recommended ranges for FFU ceiling coverage.
Terra recommends the high value within each range, which in most cases accommodates typical contamination loads presented by personnel and equipment. Modular Power Distribution Modules make it easy to add as requirements change – plug-and-play connections eliminate the need for hard-wiring by an electrician.
Cleanroom Design and Materials
A Terra Product Specialist will advise on the proper panel and other component materials to meet specific requirements for ISO compatibility, sterilization, chemical resistance, static safety, and other environmental concerns.
Environmental Control and Documentation
Adjustable exhaust vents and manual FFU speed controls on all Terra cleanrooms allow regulation of air change rates. For centralized display and control, select low-cost automated FFU speed controls, which also allow remote Building Management System (BMS) fan control and even dynamic fan adjustment in response to programmed pressure levels. Air pressure, temperature, and humidity data are logged for a traceable operating history.
Modular cleanrooms are available with stand-alone air conditioning modules or can be integrated with existing A/C systems. Humidification and De-humidification systems meet specific RH requirements.
Products Tailored to Your Cleanroom Environment
Provide Terra with your desired ISO Grade design. We will tailor the product to meet your criteria and certify it with a report appended to your invoice. Certificate includes all the necessary information to streamline audits and facility compliance.
In Stock Pre-Fabricated Cleanroom Components
Since each pre-fabricated cleanroom component is tested and stocked, room pre-assembly is no longer required. Our lead times consist solely of the time it takes draw, package and ship the components to you.
Long Running FFU Motors
Terra’s filter fan unit motors are rated for 5 years of continuous, 24/7 operation, if the HEPA filters are consistently replaced. To accurately monitor your HEPA filter’s saturation levels, purchase Terra’s audible and visual filter replacement alarm system.
Optional Raised Flooring
Raised flooring is ideal for cleanroom classifications below ISO 5 to optimize vertical laminar fow.
Interchangeable Panels for Quick Install
Wall panels are mounted by clean and attractive mirror-finished stainless steel L-brackets that clamp the panel in place, creating a showcase cleanroom and allowing panel change-out in minutes, with no special tools.
Adjustable IsoVents™ Help Balance Differential Pressure
Cleanroom wall panels include adjustable exhaust vents to help balance differential room pressure to achieve the desired ISO requirements.
Multi-Suite Hardwall Modular Cleanroom
Economical modular construction is ideal for multiple cleanroom suites with cascading pressures and ISO cleanliness levels. Rigid steel frame supports sections up to 30 feet wide without internal support columns or ceiling suspension cables.
Air Conditioning/RH Control
Modular Hardwall Cleanrooms are available with modular air conditioning modules or can be integrated into existing facility A/C system, as shown here.
Application-Specific Doors
Select aluminum, stainless steel frame or frameless cleanroom-rated doors with tempered glass, polycarbonate, acylic or dissipative PVC panels (shown: SS frame with polycarbonate panel).
Cleanroom LED Light Panel with Emergency Power Supply, 2' x 2'
Cleanroom LED lights are equipped with emergency back-up batteries to ensure continued operation in the event of a power failure.
Seismic Safe Cleanroom Design
Terra’s modular cleanrooms are designed with seismic safety in mind. Rigid steel frames and ceiling grids are designed with sufficient factors of safety to provide vertical and lateral strength recommended by professional engineers. Both hardwall and softwall designs can be installed to adhere to local seismic codes. Optional seismic and structural calculations can be drafted and stamped by a licensed PE to help meet municipal permitting requirements.
High-Throughput Cleanroom Manufacturing
Over the past 5 years, Terra has manufactured nearly 1,500 UL-approved cleanrooms at industry-leading build times. Terra’s versatile modular cleanroom frame and panel designs adapt to any floor plan requirement. The UL-rated and scalable plug-and-play power distribution system further simplifies installment of FFU's and lights to cleanrooms of any size.
Clean and Durable Powder Coat Finish
Terra’s signature white powder coat finish provides a high quality, durable barrier to protect against corrosion, plus a clean and attractive aesthetic. The advanced heat-fused formulation exceeds ASTM and ISO paint standards to resist chipping, scratching, fading, and wearing.
4,000 Worldwide Cleanrooms
Since 1976, Terra has designed and manufactured over 4,000 cleanrooms for companies at the leading edge of high technology
Manufacturer, Distributor and Service Provider
Terra is not just a product manufacturer, we provide a suite of services to help our customers navigate the complex process of ensuring their equipment is operational
On a tight schedule?Choose FasTrak 24/7 Priority Service to help meet your critical schedule for Terra-manufactured products, either before or after your order is placed.*
FasTrak 24/7 provides a 24/7 commitment to meet the shipping date YOU specify, regardless of quoted lead times.
FasTrak 24/7 assigns a dedicated production team plus a dedicated senior expeditor working three shifts to meet your delivery specification.
FasTrak 24/7 guarantees* to meet the agreed-to specified ship date.
Call for pricing. FasTrak service fees cover costs of additional services only, without additional profit.
* Terra's FasTrak services limited guarantee: to ship on the ESD or date specified OR to refund up to 100% of FasTrak charges. This guarantee covers no direct, special, consequential or other damages and is strictly limited to up to 100% of the amount paid for FasTrak service. When a specified ship date is missed due to factors outside Terra's control (vendor performance, deliveries by shipping companies, etc.) and random factors such as accidents, the credit of up to 100% of the FasTrak 24/7 may not apply. FasTrak service requested after order placement will be quoted and accepted based on available time remaining before required ship date.