Terra Universal’s cleanroom doors are designed for quick and easy installation into operating rooms, surgical suites, stick-built or modular cleanrooms. Designed for health care, pharmaceutical, and CGMP facilities, Terra’s cleanroom doors are easy-to-sterilize, maintain room pressure and resist common biocides and hospital-grade disinfectants.
Terra Universal’s cleanroom windows are designed for quick and easy installation into stick-built or modular cleanrooms. Configured for health care, pharmaceutical, and CGMP facilities, Terra’s cleanroom windows are easy-to-clean, hygienic, support aseptic environments and enhance the visibility of operations and foot traffic.
Terra’s broad portfolio of cleanroom window designs includes flush-mount, crevice-free, frameless BioSafe windows, economical, framed ValuLine windows, and special-application designs including UL-listed and fire-rated windows. Switch Glass windows and internal blinds are optional for high privacy areas.
Cleanroom monitoring systems are quickly becoming a feature expected for all modular cleanrooms, especially given the cGMP and GLP requirements for environmental reporting.
Not every facility requires arrays of sensors for temperature, particulate, humidity, and pressure differential. The cost of a monitoring system is derived from several factors including the number and type of sensors, sampling rate, instrument sensitivity, and any value-added features such as WIFI, alarms, and automation of feedback controls. Determining the best option requires balancing a facility's needs today with the possibility of growth and expansion years down the line.
In the United States, ISO 14644-1 is regarded as the gold standard for cleanroom construction. Cleanroom standards help define and measure expected outcomes but do not always provide a clear roadmap on how to achieve them. In parallel, GMP, IEST, USP, EU, and ASHRAE standards may provide more specific methodologies for air quality classification, testing equipment, and validation methods.
The cleanroom ceiling grid (shown above) is completely filled with HEPA-filtered fan units, lights, and ceiling tiles. A construction team installing or retrofitting this room – whether the room is stick-built or modular – will face major challenges. Each FFU and light must be individually hard-wired for operation; since the ceiling isn’t walkable, this task is costly, labor-intensive, and inefficient. A cleanroom maintenance crew will face similar obstacles in the event of room reconfiguration or relocation, or FFU change-out and filter replacement.
Compare cleanroom fan filter types and FFU features including airflow design, size, motors, construction, control systems, and compatible accessories.
Laminar flow air and positive pressure cleanroom design are ideal for non-hazardous, ultra-clean applications. Positive pressure mitigates dirt from entering the cleanroom when opening doors or pass-through chambers. Laminar airflow design ensures that air maintains a singular, uniform direction and velocity from intake to exhaust port. Terra's positive pressure cleanrooms include HEPA filtration systems capable of ISO Class 3 - ISO Class 8 air quality conditions. ULPA filtration units are available for the most sensitive ISO 3 - ISO 5 product applications including pharmaceutical compounding, semiconductor wafer processing, sterile packaging, and micro-nanofabrication.
The difference between isolation and containment typically identifies the type of airflow design within the environment. In practice, a cleanroom may require both positive and negative pressure systems within a single cleanroom suite.
- An isolation cleanroom is a positive pressure room appropriate for ultra-clean processes, aseptic workflows, pharmaceutical compounding, and biologically sensitive applications.
- A containment cleanroom is a negative or neutral pressure room that typically exhausts contaminated air to an outside area to prevent operational exposure to toxic, potent, or noxious substances.
Terra's latest passthrough chamber designs feature a closed-loop HEPA filtration module and dozens of readily integrated smart features. In meticulously regulated industries, passthrough chambers with integrated HEPA filtration are essential for flushing stagnant air and maintaining low particulate within a transfer box enclosure.
Check out our list of Dos and Don’ts in a cleanroom, a summary of cleanroom best practices for making the controlled environment function at peak performance. These are good resources for new cleanroom operators or those unsure about what steps to take in a cleanroom environment.
