A Lithium-Ion battery consists of a cathode, anode, current collectors, and a porous separator that prevents shorting of the anode and cathode. As the Li-ion cell discharges energy, there is a significant increase in both temperature and the pressure exerted by the reaction. These two factors have the potential to result in a runaway chemical reaction, and ultimately an explosion. Thus, calorimeters must measure both temperature and pressure changes that occur to identify anomalies and prevent dangerous situations.
Use this glovebox features comparison chart to help choose the best glovebox system for your application and budget.
Inert nitrogen gas is commonly used in laboratories to control the atmosphere for highly sensitive equipment and procedures. The best way to maintain the environment in a desiccator cabinet, glove box, or similar enclosure, is to automatically purge the environment with nitrogen or argon gas. Because these processes happen automatically based on humidity set-points, smart controllers and sensors allow for more trackable, traceable, and efficient results.
Forget about renting nitrogen tanks — laboratory applications aren’t on the same level as buying helium for a kid’s birthday balloons. Critical operations can’t wait for resupply. What happens when production stops because the gas supply has depleted, or when valuable experiments or products are ruined because of moisture exposure? As far as the old-fashioned nitrogen delivery via tank and truck, why wait to have crucial laboratory supplies left on the cleanroom stoop like old milk bottles? How much time should personnel have to spend refilling each tank? And where in the space-starved facility should the bulky supplies wait for use?
Additive manufacturing (AM), commonly called 3D printing, isn’t just for rocket scientists anymore. Its use has increased exponentially as companies and researchers discover useful applications and innovative methods. Availability of equipment and supplies for performing three-dimensional printing is becoming almost commonplace; it’s just a matter of time before retailers start to offer 3D printing services, or a few mavericks begin to do it in their homes (broken coffee cup? No problem; I’ll just make another one!).
Back in the late 1980s, single-production industrial prototyping was going from drawing board to reality. The first patent was issued in 1986 for the stereolithography apparatus (SLA), with the first
Prominently featured in the pharmaceutical manufacturing industry, a barrier isolator creates an aseptic environment for compounding parenteral (injectable), ophthalmic, and inhaled medications. Due to the significant risk posed by microbiological contamination, the critical area where the compounding takes place requires protection beyond that of a typical laboratory glovebox.
Since the first publication of USP’s General Chapter <797> Pharmaceutical Compounding—Sterile Preparations, compounding aseptic isolators (CAI) have offered the most economical alternative to constructing a dedicated cleanroom for sterile compounding. However, pharmaceutical compounding standards have undergone a major overhaul in recent years, including a developing revision of USP 797.
Below are the answers to three common questions regarding the future of isolators in compounding pharmacies.
Glove boxes were first used in the 1940s as controlled environments for the military to research radioactive materials. These special controlled environments increased in popularity as the medical field began handling viruses and other pathogens for the creation of vaccines and pharmaceuticals.
These days, a number of glove box configurations are used in even more unimaginable ways that impact our lives. The following are just a few surprising glove box practices.
Sometimes a controlled environment becomes a necessity during the performance of experiments or the handling of certain materials. When this happens, a special device, called an isolation glove box, allows researchers to perform their tasks with materials kept in strict isolation. The positive-pressure box shields materials from damaging environmental elements such as moisture.
But what exactly is a glove box? As its name suggests, it is a sealed box manufactured using materials such as acrylic, static-dissipative PVC or stainless steel that includes two or more gloves, used to handle the contents within. While there are several types of glove boxes, the basic premise behind them all is the same…to give the user the ability to handle substances or objects without breaking strict isolation protocols.
The two main types of glove boxes are “Isolation” and “containment.” The difference depends on what needs