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Barrier—A physical separation of a material from the ambient environment. Barriers must be evaluated for their effectiveness in specific applications. For example, plastics may form effective, inexpensive particulate barriers, but are permeable to water vapor.
Enclosure—A multi-sided barrier that effectively isolates the process environment from the ambient environment. Hoods and open-front chambers are non-isolated enclosures that rely on careful management of air flow to protect either the process or ambient environment. Glove boxes are isolated enclosures.
Dry Box—An enclosure that maintains a low-humidity environment, either through use of a dry purge gas (such as nitrogen, argon, or clean, dry air) or a desiccant. Glove boxes are dry boxes with sealed glove ports that allow an operator to manipulate isolated material and equipment. Desiccators are dry boxes without arm ports that are used primarily for storage or drying/degassing.
Isolation Glove Box—A glove box that protects materials or processes from the operator and/or the ambient environment. Isolation glove boxes may be configured to prevent specific kinds of exposure (to humidity, particles, static charges, low or high temperature, etc.). Terra glove boxes achieve this isolation through a variety of environmental control modules, including inert-gas controllers that maintain a continuous low-level positive pressure (see overview above).
Containment Glove Box—A glove box that protects the operator and/or ambient environment from the material or process inside the glove box. Containment glove boxes are commonly used to isolate hazardous materials in the pharmaceutical, biological, and nuclear industries.
Containment Glove Box—A glove box that protects the operator and ambient environment from materials or processes inside the glove box. In a positive-pressure application, air-tight seals protect the ambient environment from exposure to hazardous or toxic materials, but purged gas may require containment or treatment to prevent contamination. In negative-pressure applications, hazardous powders, vapors or fumes are ducted from the glove box or treated with an appropriate filter (particulate or vapor) to allow safe release.
Controlled Environment Glove Box—A glove box (either isolation or containment) that meets precise requirements for humidity, temperature, static safety, particulates, and/or other environmental conditions. Typically, such enclosures operate under a positive pressure of inert process gas or a negative pressure for fume or other contaminant removal.
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Minienvironment—This term is broadly used in the same sense as "enclosure." However, it suggests specially configured enclosures that accommodate industry-specific automated process equipment, such as semiconductor probers or package sealers, or that facilitate robotic transfer of specialized containers, such as reticle pods.
Barrier Isolator (Isolator or Isolation Barrier)—An enclosure that protects both the process and the ambient environment. These industry-specific terms emphasize the need to maintain an absolute environmental barrier and to facilitate effective cleaning or sterilization, especially in pharmaceutical applications. Barrier isolators typically minimize cracks and crevices, where contaminants can collect, and feature radius seams and corners that are easy to sterilize.
Air Lock—A pass-through chamber used for transfer of small objects into and out of a glove box with minimal disruption of the controlled glove box environment. Also called a Transfer Chamber or Antechamber. Specialized air lock ports, such as Bag-In, Bag-Out Ports, further protect the external environment from hazardous vapors or powders inside a Containment Glove Box. Terra air locks feature connections to facilitate purging with an inert process gas. Interlocks are available on an optional basis to minimize cross-contamination.
Bag-In, Bag-Out Port—A specialized port on a glove box or air lock that allows materials to be packaged with a barrier material (film or foil) before they are removed from a glove box.
Process Gas—A gas used to displace ambient air inside an enclosure. Generally, engineers base their selection of a process gas (or "purge gas") on its ability to retard chemical reaction, especially oxidation. Nitrogen is the most common process gas because it is inert, nontoxic, noncombustible, and relatively inexpensive. Trace gas mixtures, often including helium, are used in package sealing to allow subsequent leak testing in a vacuum chamber. Oxygen analyzers are used to ensure that oxygen levels in a process chamber remain below acceptable concentrations (often < 1 part per million by volume).
WC (Water Column)/ WG (Water Gauge)—a scale used to measure low-level negative pressure (e.g., 1" WG = pressure necessary to raise a column of water in a water gauge 1" = 9.869 x 10-1" Hg).
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